Description
Ibruxen 140mg (active ingredient Ibrutinib) is a targeted oral chemotherapy medication used to treat various blood cancers, including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), marginal zone lymphoma (MZL), and Waldenström’s macroglobulinemia. It works by inhibiting a specific enzyme called Bruton’s tyrosine kinase (BTK), which helps slow or stop the growth of cancer cells. [1, 2]
Key Details & Dosage
- Class: Targeted therapy, BTK inhibitor. [1]
- Manufacturer: Manufactured by Everest Pharmaceuticals (generically known as Ibrutinib). [1]
- General Dosage:
- MCL and MZL: 560 mg (four capsules) once daily.
- CLL, SLL, and Waldenström’s: 420 mg (three capsules) once daily. [1]
Important Precautions
- Dietary Restrictions: Avoid eating grapefruit or drinking grapefruit juice, as well as consuming Seville oranges, as these can increase the level of the drug in your blood. [1]
- Bleeding Risk: Ibrutinib can increase your risk of serious bleeding. Inform your doctor about any bleeding disorders or if you are taking blood thinners. [1]
- Pregnancy: It should not be used during pregnancy as it can harm an unborn baby. [1]
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